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(6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one
- Development stage
- Preclinical
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the biphenyl class of organic compounds. It is identified as an experimental drug and has been studied primarily as a β-secretase 1 (BACE1) inhibitor. BACE1 inhibitors are being investigated for their potential in treating Alzheimer's disease by reducing amyloid-beta production through inhibition of the enzyme responsible for its generation. The compound is not approved for clinical use and remains at the preclinical or experimental stage[1][4][7].
- Other names
- (6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one(6R)-2-amino-6-{2-[3-(3-methoxyphenyl)phenyl]ethyl}-3,6-dimethyl-tetrahydropyrimidinone4(3H)-Pyrimidinone, 2-amino–5,6-dihydro–[1,1′–biphenyl] derivative
02
Targets
BACE1 (Beta-site APP-cleaving enzyme 1)
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